AKOS BRN-0586

AKOS BRN-0586 - Names and Identifiers

Name	(2-Methoxy-5-methylphenyl)boronic acid
Synonyms	AKOS BRN-0586 CHEMBRDG-BB 4008663 2-Methoxy-5-methylphenylboronicacid 5-Methyl-2-methoxyphenylboronic acid 2-Methoxy-5-Methylphenylboronic Acid 2-Methoxy-5-methylphenylboronic acid 5-METHOXY-2-METHYLPHENYL BORONIC ACID (2-Methoxy-5-methylphenyl)boronic acid BORONICACID, (2-METHOXY-5-METHYLPHENYL)- (9CI) 2-Methoxy-5-Methylphenylboronic Acid (contains varying aMounts of Anhydride)
CAS	127972-00-3
InChI	InChI=1/C8H11BO3/c1-6-3-4-8(12-2)7(5-6)9(10)11/h3-5,10-11H,1-2H3

AKOS BRN-0586 - Physico-chemical Properties

Molecular Formula	C8H11BO3
Molar Mass	165.98
Density	1.14±0.1 g/cm3(Predicted)
Melting Point	92-97 °C (lit.)
Boling Point	342.0±52.0 °C(Predicted)
Flash Point	160.7°C
Solubility	Soluble in methanol.
Vapor Presure	2.97E-05mmHg at 25°C
Appearance	White to white-like powder
pKa	8.65±0.58(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.52
MDL	MFCD02179465

AKOS BRN-0586 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves.
WGK Germany	3
HS Code	29319090
Hazard Class	IRRITANT

AKOS BRN-0586 - Introduction

2-methoxy-5-methylphenylboronic acid is an organic boron compound with the chemical formula C8H11BO3 and a molecular weight of 149.98g/mol. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
2-Methoxy-5-methylphenylboronic acid is a white crystalline solid with a melting point of about 160-162°C. It is less soluble in water and more soluble in organic solvents such as ethanol, methanol and dichloromethane.

Use:
2-methoxy-5-methylphenylboronic acid is mainly used as a catalyst or ligand in organic synthesis reactions. It can be used for various phenylboronic acid catalyzed reactions, such as: coupling reactions, such as Suzuki coupling reaction and Stille coupling reaction; C- H activation reactions, such as C- H functionalization reactions, such as C- H carbonylation reaction and C- H nitro reaction.

Preparation Method:
A common preparation method is to obtain 2-methoxy-5-methylphenylboronic acid by reacting p-methylphenylboronic acid and methanol. The reaction conditions may be carried out at normal temperature using hydrochloric acid or other acids as a catalyst.

Safety Information:
There is limited safety information on 2-methoxy-5-methylphenylboronic acid. However, in general, any chemical should be used and handled with caution. During the operation, appropriate laboratory safety measures should be taken, such as wearing chemical glasses, gloves and laboratory coats. Also, avoid inhalation, ingestion or contact with skin and eyes. Before use, it is best to read the relevant safety data sheet of the chemical carefully and follow the appropriate method of operation and handling. In case of misoperation or human contact, please seek medical advice immediately.

Last Update：2024-04-10 22:29:15